Weight Loss & Metabolic Health

Amlexanox

A metabolic inflammation regulator that supports fat loss, insulin sensitivity, and cellular repair.

Doctor-Prescribed

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$65.00 (capsule)

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Supports healthy fat loss and body composition

Improves insulin sensitivity and glucose metabolism

Reduces inflammation linked to metabolic dysfunction

Promotes cellular repair and energy balance

Aids in restoring optimal metabolic rhythm

What is Amlexanox?

Amlexanox 40mg is a dual anti-inflammatory and metabolic-regulating compound gaining scientific attention for its role in supporting weight management and insulin sensitivity. Initially developed to treat allergic and inflammatory conditions, Amlexanox is now being studied for its ability to inhibit key enzymes—IKKε and TBK1—that drive obesity-related inflammation and insulin resistance. By targeting these metabolic pathways, Amlexanox helps rebalance the body’s energy metabolism, reduce fat storage, and improve glucose regulation. At PeptideWebMD, Amlexanox is prescribed as part of a doctor-supervised weight loss and metabolic optimization program, ensuring safety, precision, and measurable results.

Note: This product is not approved by the FDA. It is available only via prescription under the supervision of a licensed healthcare provider.

Science & Mechanism of Action

Amlexanox works by blocking two enzymes — IKKε (I-kappa-B kinase epsilon) and TBK1 (TANK-binding kinase 1) — both known to disrupt metabolic function and promote fat accumulation.

Reduces Inflammatory Signaling

Suppresses low-grade inflammation in adipose (fat) tissue, improving metabolic balance.

Enhances Glucose Utilization

Increases insulin sensitivity and glucose uptake in cells.

Promotes Fat Metabolism

Decreases fat storage and encourages lipolysis through improved cellular energy efficiency.

Restores Mitochondrial Health

Improves cellular metabolism and reduces oxidative stress.

Benefits & Clinical Applications

Scientifically supported benefits across multiple health concerns

For Weight Management and Fat Loss

Reduces calorie storage and promotes fat utilization
Supports steady energy without stimulant-based side effects
Works synergistically with peptides like Tirzepatide or AOD 9604

For Metabolic Health

Improves insulin sensitivity and blood glucose control
Reduces chronic inflammation linked to obesity and metabolic syndrome

For Cellular Function and Longevity

Helps repair metabolically stressed cells
May reduce oxidative damage and promote healthier energy balance

Physician-Guided Protocol

Safe, effective dosing under medical supervision

For educational reference only. Actual dosage and duration are determined during consultation with a licensed physician.

Typical Treatment Protocol

Delivery Method

Oral capsule with water, taken once daily

Typical Range

25–100 mg daily, depending on protocol and patient needs

Duration

Commonly used for 8–12 weeks within supervised metabolic support plans

Note: All protocols are prescribed and monitored by licensed physicians. Dosing varies based on individual needs, injury severity, and treatment goals. Do not self-administer without medical guidance.

Safety Profile & Considerations

Transparent information about side effects and contraindications

Common Side Effects

Occasional mild nausea
headache, or gastrointestinal discomfort, typically resolving within a few days of use.

Who Should Avoid

Not recommended for individuals with autoimmune disorders or those on strong anti-inflammatory medications.
Avoid during pregnancy or breastfeeding unless prescribed by a physician. All therapies from PeptideWebMD are pharmacy-compounded, doctor-prescribed, and formulated for clinical safety.

Amlexanox targets metabolic inflammation at its root — helping patients overcome plateaus in fat loss and improve their body’s energy regulation without the side effects of stimulant-based weight loss drugs.

Dr. Jonathan Hinds, MD, FAAMFM, ABAARM Medical Director, PeptideWebMD

Frequently Asked Questions

Common questions about Amlexanox

How does Amlexanox differ from Semaglutide or AOD 9604? +

While GLP-1 peptides like Semaglutide regulate appetite and glucose response, Amlexanox directly targets inflammation-driven metabolic dysfunction, making it a complementary option.

Is it suitable for people with metabolic syndrome or insulin resistance? +

Yes. It’s being studied for improving insulin sensitivity and restoring metabolic balance in these individuals.

When are results noticeable? +

Many users report improved energy, mood, and appetite control within 1–2 weeks; measurable changes in body composition typically occur within 4–8 weeks.

Can Amlexanox be combined with other peptides or medications? +

Yes, under medical guidance. It pairs effectively with GLP-1 agonists, AOD 9604, or MOTS-c for comprehensive metabolic support.