Muscle Growth, Recovery & Performance

IGF-1 LR3

Advanced growth-factor analog that supports muscle growth, recovery, cellular repair, and performance optimization.

Doctor-Prescribed

Lab-Tested Purity

Ships to Your Door

Satisfaction Guarantee

$160.00

Stimulates muscle cell growth and regeneration for enhanced strength and performance

Promotes fat utilization while preserving lean tissue mass

Accelerates recovery and supports cellular healing at the tissue level

Encourages collagen and skin renewal for anti-aging support

Doctor-prescribed peptide therapy, compounded and fulfilled through licensed U.S. pharmacies

What is IGF-1 LR3?

IGF-1 LR3 (Insulin-Like Growth Factor 1 Long R3) is a bio-engineered analog of natural IGF-1 that exhibits greater stability and biological activity. Its “Long R3” modification allows it to remain active for up to 30 hours—providing sustained anabolic and regenerative effects that extend beyond those of native IGF-1. Medically guided IGF-1 LR3 therapy at PeptideWebMD is designed to support muscle recovery, fat metabolism, and cellular repair while maintaining balanced, evidence-based dosing protocols.

Note: This product is not approved by the FDA. It is available only via prescription under the supervision of a licensed healthcare provider.

Science & Mechanism of Action

IGF-1 LR3 binds to IGF-1 receptors within muscle, bone, and connective tissues to stimulate protein synthesis and cell proliferation. Its structural modification reduces binding to IGF-binding proteins, extending its half-life and systemic reach.

Activates Cell Growth Pathways

Promotes myoblast differentiation and muscle fiber regeneration.

Enhances Protein Synthesis

Improves nitrogen retention for lean muscle development.

Supports Metabolic Health

Facilitates fat oxidation and glucose utilization for improved energy balance.

Benefits & Clinical Applications

Scientifically supported benefits across multiple health concerns

For Muscle Growth & Performance

Increases lean muscle size and density
Enhances strength, endurance, and recovery speed
Supports post-training anabolic adaptation

For Recovery & Regeneration

Promotes tissue and nerve repair following injury or strain
Improves joint integrity and connective-tissue resilience

For Anti-Aging & Cellular Support

Boosts collagen production and skin elasticity
Supports organ and neural regeneration pathways

Physician-Guided Protocol

Safe, effective dosing under medical supervision

For educational purposes only. Precise protocols are set by your prescribing physician.

Typical Treatment Protocol

Delivery Method

Subcutaneous or intramuscular injection, often near target muscle groups

Typical Range

20–100 mcg daily, adjusted to treatment goals

Duration

4–6 weeks per phase with rest intervals as advised by your provider

Note: All protocols are prescribed and monitored by licensed physicians. Dosing varies based on individual needs, injury severity, and treatment goals. Do not self-administer without medical guidance.

Safety Profile & Considerations

Transparent information about side effects and contraindications

Common Side Effects

Transient hypoglycemia, joint stiffness, or injection-site irritation that typically resolves quickly.

Who Should Avoid

Individuals with active cancer or uncontrolled growth-related conditions should avoid use without specialist clearance.

IGF-1 LR3 is a cornerstone peptide for muscle repair and cellular longevity. By enhancing protein synthesis and recovery, it supports patients pursuing strength, healing, and healthy aging through controlled, science-based protocols.

Dr. Jonathan Hinds, MD, FAAMFM, ABAARM Medical Director, PeptideWebMD

Frequently Asked Questions

Common questions about IGF-1 LR3

How is IGF-1 LR3 different from regular IGF-1? +

The ‘Long R3’ variant has a longer half-life and greater bioavailability, producing more sustained physiological effects.

Can IGF-1 LR3 be combined with other peptides? +

Yes. It’s often paired with CJC-1295, Ipamorelin, or TB-500 to amplify growth and recovery responses under medical supervision.

When do results appear? +

Most patients notice improvements in strength and recovery within 1–3 weeks of consistent, doctor-guided therapy.

Is it safe for long-term protocols? +

Yes, when monitored by a qualified provider to avoid excess growth factor exposure and maintain metabolic balance.