PTD-DBM
$117.00
PTD-DBM (Protein Transduction Domain–Disheveled Binding Motif) is a synthetic peptide that targets the Wnt/β-catenin signaling pathway, a critical system involved in hair follicle development, regeneration, and stem cell activation. PTD-DBM has gained attention in hair restoration research for its ability to reactivate dormant follicles, promote hair growth, and potentially reverse androgenic alopecia. Often studied in topical applications and scalp therapies, PTD-DBM is commonly combined with other compounds like valproic acid or GHK-Cu to support enhanced results. You can buy PTD- DBM online from trusted peptide suppliers for research and educational use.
Key Benefits
- Stimulates Hair Follicle Regeneration – Reactivates dormant follicles and promotes hair regrowth.
- Targets Wnt/β-Catenin Pathway – Enhances signaling required for hair cycling and stem cell renewal.
- Non-Hormonal Action – Works without altering systemic hormone levels, unlike DHT blockers.
- Topical Application Potential – Suitable for research involving direct scalp use for localized action.
- Synergistic with Other Hair Peptides – Commonly paired with GHK-Cu or other growth- stimulating agents.
Mechanism of Action
- PTD-DBM inhibits CXXC5, a suppressor of the Wnt/β-catenin pathway, thereby reactivating this crucial regenerative signal.
- Wnt signaling is essential for initiating the anagen (growth) phase of the hair cycle.
- By removing the inhibition caused by CXXC5, PTD-DBM allows follicular stem cells to proliferate and promote new hair shaft development.
Dosage Recommendations
- Typical Dosage – Topical concentrations typically range from 250–500 mcg per application in research formulations.
- Administration – Most often applied topically to the scalp; may be delivered through microneedling or sprays in experimental setups.
- Cycling – Applied once daily or every other day in 4–12 week research protocols depending on hair density goals.
Research and Studies
- Studies in animal models have shown that PTD-DBM can promote significant hair regrowth and increased follicle density.
- Human scalp tissue research has confirmed its ability to enhance hair follicle activity and prolong the anagen phase.
- Research combining PTD-DBM with valproic acid has demonstrated enhanced Wnt activation and improved hair growth results.
Possible Side Effects and Contraindications
- Common Side Effects – Mild scalp irritation, redness, or itching in some research subjects.
- Precautions – Use with care on broken or highly sensitive skin; not for systemic use.
- Drug Interactions – None widely documented, but stacking with multiple active compounds should be monitored in research settings.
Storage and Handling Instructions
- Store reconstituted PTD-DBM in a refrigerator at 2–8°C (36–46°F).
- Lyophilized powder should be stored in a cool, dry, dark environment before use.
- Use sterile, clean tools when mixing or applying to maintain purity and potency.
Frequently Asked Questions (FAQs)
- Is PTD-DBM a DHT blocker?
No — it works independently of hormonal pathways, making it a non-hormonal hair growth option.
- Can PTD-DBM be used with GHK-Cu or minoxidil?
Yes, it’s often stacked in research with peptides and topical agents that support scalp circulation and regeneration.
- When do results typically appear in studies?
Some research models report visible regrowth and density improvement within 4–8 weeks of consistent application.
Medical Disclaimer
PTD-DBM is intended for research and educational purposes only. It is not approved for human consumption or to diagnose, treat, cure, or prevent any disease. Always consult a licensed healthcare provider before beginning any research protocol.
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