MOTS-c

Key Benefits

• Improves Insulin Sensitivity – Enhances glucose uptake and may help balance blood sugar levels.
• Boosts Fat Metabolism – Promotes the use of fatty acids for energy, aiding in fat loss and body composition improvement.
• Increases Cellular Energy – Supports mitochondrial function and energy production under metabolic stress.
• Enhances Exercise Endurance – Improves physical performance and recovery by optimizing energy usage.
• Anti-Aging Potential – Activates AMPK pathways, which are associated with longevity and reduced age-related decline.

Mechanism of Action

• MOTS-c activates the AMPK pathway, a cellular energy sensor that promotes energy balance and mitochondrial biogenesis.
• It enhances fatty acid oxidation and improves glucose metabolism, especially under stress or fasting conditions.
• It is also believed to help protect against oxidative stress and age-related mitochondrial dysfunction.

Dosage Recommendations

• Typical Dosage – 5–10 mg per dose, 2–3 times per week is commonly used in metabolic and performance-related research.
• Administration – Typically administered via subcutaneous injection.
• Cycling – Often used in 4–8 week cycles, especially in research on body composition, endurance, or metabolic dysfunction.

Research and Studies

• Animal studies have shown MOTS-c improves insulin sensitivity, reduces weight gain, and increases exercise capacity.
• Research supports its role in combating age-related diseases, including type 2 diabetes and obesity.
• Ongoing studies are exploring its effects on muscle aging, endurance enhancement, and mitochondrial repair.

Possible Side Effects and Contraindications

• Common Side Effects – Generally well tolerated; some subjects report mild fatigue or injection site discomfort.
• Precautions – Caution in individuals with metabolic or endocrine disorders; professional guidance is advised in advanced studies.
• Drug Interactions – May amplify effects of insulin sensitizers, fat burners, or AMPK activators.

Storage and Handling Instructions

• Store reconstituted MOTS-c in a refrigerator at 2–8°C (36–46°F).
• Keep lyophilized powder in a cool, dry, dark location until reconstitution.
• Always use sterile technique when handling and injecting to ensure peptide integrity.

Frequently Asked Questions (FAQs)

• Is MOTS-c a fat-loss peptide?

While not a stimulant, MOTS-c helps shift the body’s metabolism toward fat burning and energy efficiency.

• Does it help with workout performance?

Yes — studies show improved endurance and physical output in metabolic stress conditions.

• Can MOTS-c be stacked with other peptides?

Yes, often paired with AOD 9604, BPC-157, or metabolic enhancers for synergistic research effects.

Medical Disclaimer

MOTS-c is intended for research and educational purposes only. It is not approved for human consumption or to diagnose, treat, cure, or prevent any disease. Always consult a licensed healthcare provider before beginning any research protocol.