GHK-Cu

Key Benefits

• Skin Regeneration – Promotes collagen and elastin production, helping reduce wrinkles and improve skin firmness.
• Wound Healing – Accelerates tissue repair, angiogenesis, and re-epithelialization in damaged skin.
• Hair Growth Stimulation – Shown to improve follicle health and promote hair regrowth in thinning areas.
• Anti-Inflammatory Effects – Reduces oxidative stress and inflammation in skin and soft tissue.
• Tissue Remodeling – Assists in removing damaged proteins and regenerating healthy skin and connective tissue.

Mechanism of Action

• GHK-Cu binds copper ions and delivers them to tissues, aiding enzymatic processes essential for regeneration.
• It upregulates genes responsible for collagen synthesis, tissue repair, and antioxidant defense.
• GHK-Cu also suppresses pro-inflammatory genes and supports the breakdown of damaged or scarred extracellular matrix.

Dosage Recommendations

• Typical Dosage – Topical formulations typically use 0.05%–0.1% GHK-Cu. Injectable forms range from 1–5 mg per dose depending on the study.
• Administration – Commonly used as a cream, foam, or injectable peptide. It may also be incorporated into microneedling and scalp treatments.
• Cycling – Often used continuously or in cycles depending on application (e.g., skin repair vs. hair regrowth).

Research and Studies

• Clinical research shows GHK-Cu improves wound healing, reduces photodamage, and reverses signs of aging skin.
• In vitro studies show increased expression of genes involved in stem cell activation and tissue remodeling.
• GHK-Cu has been explored for its potential benefits in chronic inflammatory diseases and pulmonary fibrosis models.

Possible Side Effects and Contraindications

• Common Side Effects – Mild irritation or redness may occur when applied topically; rare cases of sensitivity have been reported.
• Precautions – Individuals with copper metabolism disorders (e.g., Wilson’s disease) should avoid unsupervised use.
• Drug Interactions – No major interactions reported, though concurrent use with other actives (like retinoids) may increase skin sensitivity.

Storage and Handling Instructions

• Store topical or reconstituted GHK-Cu products in a refrigerator at 2–8°C (36–46°F).
• Keep creams and foams in cool, dry places away from direct sunlight.
• Use sterile handling for injectable forms to maintain product stability and efficacy.

Frequently Asked Questions (FAQs)

• What makes GHK-Cu different from other peptides?

It is a naturally occurring peptide in human plasma with a unique ability to bind copper and promote regenerative healing processes.

• Can GHK-Cu be used on the scalp?

Yes, it’s often applied in hair serums and foams for scalp rejuvenation and hair regrowth.

• How long does it take to see results?

Visible improvements in skin texture or hair quality may begin within 2–4 weeks of consistent use.

Medical Disclaimer

GHK-Cu is intended for research and educational purposes only. It is not approved for human consumption or to diagnose, treat, cure, or prevent any disease. Always consult a licensed healthcare provider before beginning any research protocol.