Astressin-B

Key Benefits

• Stress Regulation – Inhibits CRF receptors to help regulate cortisol and buffer the body’s response to stress.
• Hair Growth Support – Shown in studies to reverse stress-related hair loss and promote regrowth.
• Anti-Inflammatory Effects – May reduce chronic inflammation driven by elevated cortisol or HPA overactivation.
• Neuroprotective Potential – Early research suggests possible benefits for cognitive health and mood regulation under stress.
• Adrenal Support – Helps modulate the stress-response loop between the brain and adrenal glands.

Mechanism of Action

• Astressin-B blocks CRF type 1 and type 2 receptors, which are involved in the HPA axis’ stress response.
• This action reduces excessive cortisol secretion and the downstream effects of prolonged stress exposure.
• By disrupting the stress-hormone feedback loop, it may help normalize physiological processes impacted by chronic stress, including hair follicle cycling and inflammation.

Dosage Recommendations

• Typical Dosage – Research doses typically range between 10–20 mcg/kg, depending on the application.
• Administration – Commonly used via subcutaneous injection in animal or laboratory models.
• Cycling – As it targets the HPA axis, cycling strategies may vary depending on research goals. Professional oversight is recommended.

Research and Studies

• Animal studies have shown that Astressin-B can reverse alopecia (hair loss) caused by stress, with hair regrowth observed within days.
• Research suggests CRF antagonism may have implications for mood disorders, gastrointestinal function, and metabolic regulation.
• Further studies are being conducted to explore its potential therapeutic use in humans for stress-related conditions.

Possible Side Effects and Contraindications

• Common Side Effects – Minimal data available; some users report localized irritation at injection site in research settings.
• Precautions – Not recommended for use in individuals with endocrine disorders or on corticosteroid therapy unless guided by a professional.
• Drug Interactions – May alter the effects of medications that act on the adrenal or nervous system.

Storage and Handling Instructions

• Store reconstituted Astressin-B in a refrigerator at 2–8°C (36–46°F).
• Keep lyophilized powder in a cool, dry, and dark location until use.
• Avoid contamination by using sterile technique and single-use vials where possible.

Frequently Asked Questions (FAQs)

• Is Astressin-B used for hair regrowth?
  Yes, in animal models, it has shown strong potential in reversing stress-induced hair loss.
• How quickly does it work?
  Hair regrowth effects in studies began within 5 days. Stress-related hormone regulation may vary by individual or research model.
• Can it be stacked with other peptides?
  It’s sometimes combined with peptides like BPC-157 or Thymosin Beta-4 in research, but stacking should be approached cautiously.

Medical Disclaimer

Astressin-B is intended for research and educational purposes only. It is not approved for human consumption or to diagnose, treat, cure, or prevent any disease. Always consult a licensed healthcare provider before beginning any research protocol.