Semax

Key Benefits

• Cognitive Enhancement – Improves memory, learning, attention, and mental clarity.
• Neuroprotection – Helps safeguard neurons from oxidative stress, ischemia, and inflammation.
• Mood and Stress Regulation – Modulates neurotransmitters such as dopamine and serotonin.
• Supports Recovery – Assists in brain rehabilitation after trauma, stroke, or neurodegenerative decline.
• Increases BDNF Levels – Promotes brain plasticity and long-term memory formation through BDNF upregulation.

Mechanism of Action

• Semax stimulates the production of brain-derived neurotrophic factor (BDNF) and
• neurotrophin-3, which support neuroplasticity and regeneration.
• It modulates dopaminergic and serotonergic systems, enhancing focus and mood without overstimulation.
• It also exhibits antioxidant and anti-inflammatory activity in neural tissue, supporting long-term brain health.

Dosage Recommendations

• Typical Dosage – 300–600 mcg per dose, up to 2–3 times daily in cognitive or neurological research.
• Administration – Commonly delivered via intranasal spray for rapid CNS access; subcutaneous forms are also studied.
• Cycling – Often used in 5–10 day cycles for acute cognitive support or extended use for chronic recovery protocols.

Research and Studies

• Clinical studies in Russia have demonstrated improvements in memory, attention, and brain function in post-stroke patients and those with cognitive disorders.
• Animal research shows Semax reduces brain inflammation, improves neuroregeneration, and enhances adaptability to stress.
• Studied alongside Selank for synergistic benefits in mood, learning, and stress resilience.

Possible Side Effects and Contraindications

• Common Side Effects – Generally well-tolerated; rare reports of mild headache, nasal irritation, or restlessness.
• Precautions – Use with caution in subjects with psychiatric disorders or seizure history without proper oversight.
• Drug Interactions – May amplify effects of other nootropics or stimulants; best used alone or in controlled stack protocols.

Storage and Handling Instructions

• Store reconstituted Semax in a refrigerator at 2–8°C (36–46°F).
• Lyophilized powder should be kept in a cool, dry, and dark environment before use.
• Ensure nasal spray applicators are clean and sealed properly for repeated dosing.

Frequently Asked Questions (FAQs)

• What is the difference between Semax and Selank?

Semax is more focused on cognitive enhancement and neuroprotection, while Selank emphasizes anxiolytic and immune-modulating effects. They are often used together.

• Can Semax be used long-term?

Research supports both acute and extended use protocols, though breaks are often included to assess continued need and response.

• How fast do results appear in studies?

Some subjects report improved focus and clarity within hours, with cognitive and emotional benefits becoming more noticeable over several days.

Medical Disclaimer
Semax is intended for research and educational purposes only. It is not approved for human consumption or to diagnose, treat, cure, or prevent any disease. Always consult a licensed healthcare provider before beginning any research protocol.