Melanotan II

Key Benefits

• Increased Skin Pigmentation – Stimulates melanin production, leading to a natural tanning effect.
• UV Protection – May reduce sunburn risk by darkening skin and increasing its tolerance to UV exposure.
• Libido Enhancement – Known to increase sexual desire and arousal in both men and women.
• Erectile Function Support – Shown to improve erectile quality and response in clinical research.
• Appetite Regulation – Some users report reduced hunger and improved body composition during use.

Mechanism of Action

• Melanotan II binds to melanocortin receptors (MC1R for skin pigmentation and MC4R for sexual function).
• It stimulates melanogenesis, the process of melanin production in skin cells (melanocytes).
• Its action on MC4R also influences libido, appetite, and energy balance.

Dosage Recommendations

• Typical Dosage – 250–500 mcg per day is common in research, gradually titrated based on skin response or study objectives.
• Administration – Delivered via subcutaneous injection, usually in the abdomen or fatty tissue.
• Cycling – Initial loading phase followed by maintenance dosing 2–3 times per week in pigmentation research models.

Research and Studies

• Studies have shown effective tanning and photoprotection in light-skinned individuals using Melanotan II.
• Research supports its role in treating erectile dysfunction and hypoactive sexual desire disorder.
• Investigated for potential benefits in skin cancer prevention, particularly in fair-skinned populations with UV sensitivity.

Possible Side Effects and Contraindications

• Common Side Effects – Nausea, facial flushing, increased libido, darkening of moles or freckles, and mild fatigue.
• Precautions – Should not be used in individuals with a history of melanoma or severe pigment disorders without medical oversight.
• Drug Interactions – Use caution when combined with other melanocortin-stimulating agents or sexual performance enhancers.

Storage and Handling Instructions

• Store reconstituted Melanotan II in a refrigerator at 2–8°C (36–46°F).
• Lyophilized powder should be kept in a cool, dry, dark place until reconstitution.
• Use sterile technique for mixing and administering the peptide to ensure safety and effectiveness.

Frequently Asked Questions (FAQs)

• How long does it take to see tanning effects?

Skin darkening typically begins within 1–2 weeks, with full effects over 3–4 weeks of consistent use.

• Does Melanotan II work without sun exposure?

Yes, but mild UV exposure accelerates and deepens the tanning results.

• Is Melanotan II only used for tanning?

No — it’s also studied for libido, erectile function, and photoprotection benefits.

Medical Disclaimer

Melanotan II is intended for research and educational purposes only. It is not approved for human consumption or to diagnose, treat, cure, or prevent any disease. Always consult a licensed healthcare provider before beginning any research protocol.