LL-37
$195.00
LL-37 is a powerful antimicrobial and immunomodulatory peptide that plays a vital role in the body’s first line of defense against pathogens. Naturally produced in humans as part of the innate immune system, LL-37 exhibits broad-spectrum antibacterial, antiviral, and antifungal activity, while also promoting wound healing and modulating inflammation. It is widely researched for its applications in chronic infections, skin repair, and immune system support. LL-37 is especially valuable in research focused on infection resistance, autoimmune regulation, and tissue regeneration. You can buy LL-37 online from reputable peptide suppliers for research and educational purposes.
Key Benefits
- Antimicrobial Defense – Effective against bacteria, viruses, and fungi by disrupting microbial membranes.
- Immune Modulation – Balances pro- and anti-inflammatory responses to prevent overactivation.
- Wound Healing Support – Enhances tissue repair, angiogenesis, and re-epithelialization in skin and mucosal wounds.
- Antiviral Research Potential – Studied for its ability to inhibit viral entry and replication.
- Skin & Respiratory Health – Explored for topical applications in psoriasis, eczema, and lung conditions like asthma or chronic bronchitis.
Mechanism of Action
- LL-37 binds to microbial membranes, creating pores that disrupt pathogen integrity and lead to cell death.
- It interacts with immune receptors like TLRs (Toll-like receptors) to modulate cytokine production and immune activation.
- Promotes migration and proliferation of keratinocytes and fibroblasts, accelerating tissue regeneration and repair.
Dosage Recommendations
- Typical Dosage – Research protocols range from 100–500 mcg daily depending on condition and delivery method.
- Administration – Can be delivered via subcutaneous injection, topical application, or intranasal routes in respiratory studies.
- Cycling – May be used continuously or in response to specific immune or healing challenges in research.
Research and Studies
- Studies confirm LL-37’s potent antimicrobial activity against MRSA, E. coli, Candida, and Influenza A.
- Animal and human models show accelerated wound healing and reduced scarring with topical or injectable LL-37.
- Investigated in chronic inflammatory diseases, including ulcerative colitis, COPD, and autoimmune skin disorders.
Possible Side Effects and Contraindications
- Common Side Effects – Temporary redness or irritation at injection or application site may occur.
- Precautions – In autoimmune or hyperinflammatory conditions, dosage should be closely monitored to avoid immune overstimulation.
- Drug Interactions – Not recommended to combine with strong immunosuppressants or corticosteroids unless supervised.
Storage and Handling Instructions
- Store reconstituted LL-37 in a refrigerator at 2–8°C (36–46°F).
- Keep lyophilized powder in a cool, dry, and dark place before use.
- Use sterile technique during reconstitution and application to preserve stability.
Frequently Asked Questions (FAQs)
- Is LL-37 an antibiotic?
No, it is a natural host defense peptide with broad antimicrobial properties, without contributing to antibiotic resistance.
- Can it be used topically for wounds or skin conditions?
Yes, LL-37 has been shown to improve healing in skin ulcers, burns, and dermatitis in topical research models.
- Does LL-37 boost the immune system?
It modulates immune responses — enhancing pathogen defense while also preventing excessive inflammation.
Medical Disclaimer
LL-37 is intended for research and educational purposes only. It is not approved for human consumption or to diagnose, treat, cure, or prevent any disease. Always consult a licensed healthcare provider before beginning any research protocol.
Related products
