Muscle Growth, Recovery & Performance

PTD-DBM

A breakthrough peptide designed to reactivate dormant hair follicles and support natural hair regeneration.

Doctor-Prescribed

Lab-Tested Purity

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$90.00 (vial)

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Promotes natural hair growth and follicle regeneration

Activates the Wnt/β-catenin pathway for stem cell renewal

Non-hormonal mechanism — does not alter DHT or testosterone levels

Suitable for topical or microneedling-based delivery

Can be paired with GHK-Cu or Valproic Acid for enhanced results

What is PTD-DBM?

PTD-DBM (Protein Transduction Domain–Disheveled Binding Motif) is an innovative peptide developed to reactivate hair follicle stem cells through modulation of the Wnt/β-catenin signaling pathway — a key biological system controlling follicle development and regeneration. Unlike DHT blockers or hormonal treatments, PTD-DBM works by directly targeting cellular communication at the follicular level, making it a non-hormonal, regenerative approach to hair restoration. At PeptideWebMD, PTD-DBM therapy is prescribed through a doctor-guided telehealth consultation, ensuring personalized dosage, clinical oversight, and optimized results for individuals experiencing hair thinning, pattern loss, or post-stress shedding.

Note: This product is not approved by the FDA. It is available only via prescription under the supervision of a licensed healthcare provider.

Science & Mechanism of Action

The Wnt/β-catenin pathway plays a critical role in controlling hair growth cycles and stem cell activation. PTD-DBM acts as a CXXC5 inhibitor, reactivating this suppressed signaling system. This mechanism allows PTD-DBM to promote thicker, denser hair growth without influencing hormones or systemic metabolism.

Blocks CXXC5 Suppression

Prevents CXXC5 from binding to Disheveled protein, re-initiating Wnt signaling.

Reactivates Follicular Stem Cells

Stimulates stem cell proliferation and transition into the anagen (growth) phase.

Promotes Hair Shaft Formation

Encourages structural protein production necessary for healthy hair development.

Supports Scalp Regeneration

Enhances local cellular repair and vascularization in the scalp microenvironment.

Benefits & Clinical Applications

Scientifically supported benefits across multiple health concerns

For Hair Regeneration

Revives dormant or miniaturized hair follicles
Extends the anagen phase and reduces shedding
Encourages stronger, more resilient hair strands

For Scalp Health

Stimulates microcirculation and cellular oxygenation
Supports repair in post-inflammatory or stressed scalp conditions
Reduces oxidative damage linked to hair thinning

For Combination Therapy

Can be paired with GHK-Cu, Valproic Acid, or Microneedling for synergistic follicle activation
Complements peptide-based anti-aging or restorative protocols

Physician-Guided Protocol

Safe, effective dosing under medical supervision

For educational reference only. All dosages and delivery routes are determined during medical consultation.

Typical Treatment Protocol

Delivery Method

Applied directly to the scalp; may be delivered through microneedling or advanced topical vehicles

Typical Range

250–500 mcg per topical application

Duration

8–12 weeks typical; may extend for maintenance based on clinical results

Note: All protocols are prescribed and monitored by licensed physicians. Dosing varies based on individual needs, injury severity, and treatment goals. Do not self-administer without medical guidance.

Safety Profile & Considerations

Transparent information about side effects and contraindications

Common Side Effects

Temporary scalp redness, mild irritation, or itching at application sites — generally subsides within hours.

Who Should Avoid

Not recommended for open wounds or severely irritated skin. Avoid concurrent use with harsh topical actives unless medically approved.

PTD-DBM represents a new era in hair restoration — targeting the Wnt signaling pathway at its source. It’s ideal for patients seeking natural regrowth without hormonal intervention.

Dr. Jonathan Hinds, MD, FAAMFM, ABAARM Medical Director, PeptideWebMD

Frequently Asked Questions

Common questions about PTD-DBM

Is PTD-DBM similar to Minoxidil or Finasteride? +

No. PTD-DBM works by reactivating hair follicle stem cells via Wnt signaling, not by altering hormones or blood flow.

How long until results appear? +

Clinical research shows early regrowth within 4–8 weeks, with continued improvement over 12 weeks of consistent application.

Can PTD-DBM be combined with other peptides? +

Yes. It is often used alongside GHK-Cu, B7-33, or Valproic Acid for enhanced follicular activation.

Is it suitable for both men and women? +

Yes — PTD-DBM is non-hormonal and effective for both male and female hair loss patterns.