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Melanotan II
Skin Health & Aesthetic Support

Melanotan II

A scientifically studied peptide for natural tanning, UV protection, and enhanced sexual wellness.

Doctor-Prescribed
Lab-Tested Purity
Ships to Your Door
Satisfaction Guarantee
$155.00 (vial)
Stimulates natural skin pigmentation and tanning
Helps protect against UV-related damage
Enhances sexual desire and erectile function
Supports body confidence and appearance goals
Non-hormonal and neuroactive in mechanism

What is Melanotan II?

Melanotan II is a synthetic analog of alpha-melanocyte-stimulating hormone (α-MSH) — a natural peptide responsible for regulating melanin production, skin pigmentation, and certain aspects of sexual arousal. Originally developed for skin protection and phototherapy, Melanotan II is now widely studied for its dual benefits:

  • Dermatological effects — enhancing melanin production for natural tanning and photoprotection.
  • Neurological effects — activating brain pathways linked to sexual desire and libido in both men and women.

At PeptideWebMD, Melanotan II therapy is physician-supervised, ensuring safe, customized dosing that supports skin health, confidence, and sexual vitality while minimizing unwanted side effects.

Note: This product is not approved by the FDA. It is available only via prescription under the supervision of a licensed healthcare provider.

Science & Mechanism of Action

Melanotan II interacts with melanocortin receptors found in both the skin and the brain. This unique multi-receptor action makes Melanotan II a versatile peptide — studied for applications in tanning, sexual health, and metabolic balance.

1

Activates MC1R Receptors

Stimulates melanin production in melanocytes, leading to a gradual, natural tan without excessive UV exposure.

2

Stimulates MC4R Receptors

Triggers neurological pathways associated with arousal, motivation, and sexual response.

3

Regulates Appetite & Energy

Modulates hypothalamic activity involved in energy balance and satiety.

Benefits & Clinical Applications

Scientifically supported benefits across multiple health concerns

For Skin Health & Aesthetic Support

  • Promotes even, natural skin pigmentation
  • Reduces sun sensitivity and UV damage risk
  • Enhances confidence and appearance without prolonged sun exposure

For Sexual Wellness

  • Increases libido and sexual desire in both men and women
  • Improves erectile function and arousal response
  • Non-hormonal mechanism suitable for those unresponsive to PDE5 inhibitors

For Metabolic Support

  • May aid in appetite control and body composition optimization

Physician-Guided Protocol

Safe, effective dosing under medical supervision

For educational purposes only. All treatment plans are customized following doctor consultation.

Typical Treatment Protocol

Delivery Method
Subcutaneous injection in the abdomen or fatty tissue
Typical Range
250–500 mcg daily, titrated gradually
Duration
Initial loading phase followed by 2–3 maintenance doses per week

Note: All protocols are prescribed and monitored by licensed physicians. Dosing varies based on individual needs, injury severity, and treatment goals. Do not self-administer without medical guidance.

Safety Profile & Considerations

Transparent information about side effects and contraindications

Common Side Effects

  • Temporary nausea, flushing, darkening of moles, or mild fatigue — typically subside with continued use.

Who Should Avoid

  • Not recommended for individuals with a history of melanoma, pigment disorders, or uncontrolled cardiovascular conditions.
Doctor

Melanotan II is more than a tanning peptide — it’s a neuro-hormonal regulator that influences confidence, libido, and body image from both inside and out. Its versatility makes it one of the most intriguing compounds in modern peptide therapy.

Dr. Jonathan Hinds, MD, FAAMFM, ABAARM Medical Director, PeptideWebMD

Frequently Asked Questions

Common questions about Melanotan II

How long until tanning effects appear? +

Visible pigmentation typically begins within 1–2 weeks, with optimal tone achieved in 3–4 weeks.

Does it require sun exposure? +

No. While mild UV exposure enhances the results, Melanotan II can promote pigmentation independently.

Is Melanotan II safe for both men and women? +

Yes — it’s been studied extensively in both sexes for tanning, libido enhancement, and photoprotection.

Can Melanotan II improve libido or performance? +

Yes. Its activity on melanocortin receptors supports improved sexual desire and arousal through central nervous system stimulation.